1301144-74-0Relevant articles and documents
Electrochemical C?H/N?H Functionalization for the Synthesis of Highly Functionalized (Aza)indoles
Hou, Zhong-Wei,Mao, Zhong-Yi,Zhao, Huai-Bo,Melcamu, Yared Yohannes,Lu, Xin,Song, Jinshuai,Xu, Hai-Chao
, p. 9168 - 9172 (2016)
Indoles and azaindoles are among the most important heterocycles because of their prevalence in nature and their broad utility in pharmaceutical industry. Reported herein is an unprecedented noble-metal- and oxidant-free electrochemical method for the coupling of (hetero)arylamines with tethered alkynes to synthesize highly functionalized indoles, as well as the more challenging azaindoles.