1301163-56-3Relevant articles and documents
Palladium-catalyzed oxidative cross-coupling of N-tosylhydrazones or diazoesters with terminal alkynes: A route to conjugated enynes
Zhou, Lei,Ye, Fei,Ma, Jiachen,Zhang, Yan,Wang, Jianbo
, p. 3510 - 3514 (2011/05/12)
Coming at them from another angle: In a fresh approach to the synthesis of conjugated alkynes, the palladium-catalyzed cross-coupling of N-tosylhydrazones or diazoesters with terminal alkynes provided the desired enyne products with excellent stereoselectivity (see scheme; Ts=p-toluenesulfonyl). The reaction is proposed to involve an unprecedented alkynyl migratory insertion of a palladium carbene complex. Copyright