1301256-86-9

Upstream product

• 1301256-12-1 6-(t-butyldimethylsilyloxy)benzo[b]thiophene-2-boronic acid 
• 1301256-11-0 6-(t-butyldimethylsilyloxy)benzo[b]thiophene 
• 1301256-20-1 2-[4-(N-methyl-N-Boc-amino)phenyl]-6-(t-butyldimethylsilyloxy)benzo[b]thiophene 
• 1301256-48-3 2-[4-(N-methyl-N-BOC)aminophenyl]-6-allyloxybenzothiophene 
• 1301256-57-4 2-[4-(N-methyl-N-Boc-amino)phenyl]-6-(2,3-dihydroxypropoxy)benzo[b]thiophene 
• 110-87-2 3,4-dihydro-2H-pyran 
• 1301256-69-8 2-[4-(N-methyl-N-Boc-amino)phenyl]-6-(3-methanesulfonyloxy-2-hydroxypropoxy)benzo[b]thiophene 
• 1301256-30-3 2-[4-(N-methyl-N-Boc-amino)phenyl]-6-hydroxylbenzo[b]thiophene 
• 19301-39-4 1-benzothiophen-6-ol 

Downstream Products

• 1301255-93-5 2-[4-(methylamino)phenyl]-6-(3-fluoro-2-hydroxypropoxy)benzo[b]thiophene 

Relevant academic research and scientific papers

Synthesis and evaluation of 6-(3-[18F]fluoro-2-hydroxypropyl)-substituted 2-pyridylbenzothiophenes and 2-pyridylbenzothiazoles as potential PET tracers for imaging Aβ plaques

3-[18F]Fluoro-2-hydroxypropyl substituted compounds were synthesized and evaluated as novel 18F-labeled PET tracers for imaging Aβ plaque in a living brain. All compounds exhibited high binding affinities toward the synthetic Aβ

(3-FLUORO-2-HYDROXY)PROPYL-FUNCTIONALIZED ARYL DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR THE DIAGNOSIS OR TREATMENT OF NEURODEGENERATIVE BRA

The present invention relates to (3-fluoro-2-hydroxy)propyl-functionalized aryl derivatives or to the pharmaceutically acceptable salt thereof, to a method for preparing same, and to a pharmaceutical composition containing same as active ingredients for t