130132-03-5

Upstream product

• 118682-25-0 (1S,5S)-5-Methyl-2-methylene-cyclohexanol 
• 130132-02-4 (R)-1-((S)-4-Methyl-cyclohex-1-enyl)-but-3-en-2-ol 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 130132-00-2 (4R,6S,7R,9S)-4-(tert-Butyl-dimethyl-silanyloxy)-9-methyl-7-phenylselanyl-1-oxa-spiro[5.5]undecan-2-one 
• 130131-99-6 (R)-3-(tert-Butyl-dimethyl-silanyloxy)-4-((S)-4-methyl-cyclohex-1-enyl)-butyric acid 
• 130131-98-5 (R)-3-(tert-Butyl-dimethyl-silanyloxy)-4-((S)-4-methyl-cyclohex-1-enyl)-butan-1-ol 

Relevant academic research and scientific papers

An approach to the synthesis of the hexahydronaphthalene unit of pravastatin

The aldehyde 3b is prepared from (S)-pulegone (5) by a series of highly effective transformations, including a stereospecific [2,3]-Wittig rearrangement of the allyl ether of 6, stereoselective selenolactonization of 8c, SN2′ addition to 10 and a stereospecific intramolecular ene reaction of 11b.