130146-48-4Relevant articles and documents
Chemistry and structure-activity relationships of C-17 unsaturated 18-cycloalkyl and cycloalkyl analogues of enisoprost. Identification of a promising new antiulcer prostaglandin
Collins,Gasiecki,Perkins,Gullikson,Bianchi,Kramer,Ng,Yonan,Swenton,Jones,Bauer
, p. 2784 - 2793 (2007/10/02)
A series of Δ17 unsaturated cycloalkyl and cycloalkenyl analogues of enisoprost was synthetized to investigate the effects of ω chain unsaturation on gastric antisecretory activity and diarrheogenic side effects. Of these, the 17E, 18-cyclopent