130156-84-2Relevant academic research and scientific papers
Synthesis of cyclohexenols and cycloheptenols via the regioselective reductive ring opening of oxabicyclic compounds
Lautens, Mark,Ma, Shihong,Chiu, Pauline
, p. 6478 - 6487 (2007/10/03)
The reductive ring opening of oxabicyclic compounds has been achieved. While RMgBr/MgBr2 works in a few limited substrates, diisobutylaluminum hydride reacts with oxabicyclic[3.2.1]- and -[2.2.1]alkenes to provide cycloheptenols and cyclohexeno
Preparation of cyclohexenyl derivatives by the ring-opening reactions of oxabicyclo[2.2.1] compounds with cuprates
Lautens, Mark,Catherine Smith,Abd-El-Aziz, Alaa S.,Huboux, Alexandre H.
, p. 3253 - 3256 (2007/10/02)
The ring-opening reaction of 7-oxabicyclo[2.2.1]hept-5-enes with cuprates is described. SN2′ attack with retention of configuration is the predominant pathway.
