1301601-34-2Relevant academic research and scientific papers
Steering reaction pathways: From benzyl Claisen rearrangements to powerful ionic shifts
Valerio, Viviana,Madelaine, Claire,Maulide, Nuno
supporting information; experimental part, p. 4742 - 4745 (2011/05/19)
Take a walk on the wild side: A novel benzyl Claisen cascade rearrangement of keteniminium salts is described. The reaction leads to α-arylated lactones under metal-free conditions (top scheme; Tf=trifluoromethanesulfonyl). It is further demonstrated that the cationic intermediates involved can be steered away from pericyclic reaction manifolds into powerful ionic shifts through reaction design (bottom scheme). Copyright
