1301679-95-7

Upstream product

• 58801-71-1 gregatin B 
• 1301680-29-4 (2S,3R)-2-ethynyl-2,3,4,5-tetrahydro-5,5-dimethoxy-2-methylfuran-3-ol 
• 1266113-94-3 (S)-2-[(E,E)-hexa-1,3-dienyl]-5-methoxy-2-methylfuran-3(2H)-one 
• 1301680-13-6 (S)-2-[(E,E)-hexa-1,3-dienyl]-4-(1-hydroxyethyl)-5-methoxy-2-methylfuran-3(2H)-one 
• 1301680-10-3 (2S,3S)-2-[(E,E)-hexa-1,3-dienyl]-2,3,4,5-tetrahydro-5,5-dimethoxy-2-methylfuran-3-ol 
• 1301680-34-1 (2S,3R)-2-[(E,E)-hexa-1,3-dienyl]-2,3,4,5-tetrahydro-5,5-dimethoxy-2-methylfuran-3-ol 
• 1301680-08-9 (2S,3S)-2,3,4,5-tetrahydro-5,5-dimethoxy-2-methyl-2-[(E)-2-(tributylstannyl)vinyl]furan-3-ol 
• 1301680-06-7 (2S,3S)-2-[(E)-2-bromovinyl]-2,3,4,5-tetrahydro-5,5-dimethoxy-2-methylfuran-3-ol 
• 1301680-33-0 (2S,3R)-2-[(E)-2-bromovinyl]-2,3,4,5-tetrahydro-5,5-dimethoxy-2-methylfuran-3-ol 

Relevant academic research and scientific papers

A serendipitous synthesis of (+)-gregatin B, second structure revisions of the aspertetronins, gregatins, and graminin A, structure revision of the penicilliols

A (DHQN)2AQN-promoted asymmetric dihydroxylation (92% ee) of the allyl chloride derived from enynol (E)-13 and an 8-step sequence provided access to the hydroxyethylated furanone (R)-21. Oxidation with MnO2 furnished 50% furanone (+)