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1301696-45-6

4-hydroxymethyl-4-[2-(3-iodo-4-octylphenyl)ethyl]oxazolidin-2-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1301696-45-6 Structure

  • Basic information

    1. Product Name: 4-hydroxymethyl-4-[2-(3-iodo-4-octylphenyl)ethyl]oxazolidin-2-one
    2. Synonyms: 4-hydroxymethyl-4-[2-(3-iodo-4-octylphenyl)ethyl]oxazolidin-2-one
    3. CAS NO:1301696-45-6
    4. Molecular Formula:
    5. Molecular Weight: 459.368
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1301696-45-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-hydroxymethyl-4-[2-(3-iodo-4-octylphenyl)ethyl]oxazolidin-2-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-hydroxymethyl-4-[2-(3-iodo-4-octylphenyl)ethyl]oxazolidin-2-one(1301696-45-6)
    11. EPA Substance Registry System: 4-hydroxymethyl-4-[2-(3-iodo-4-octylphenyl)ethyl]oxazolidin-2-one(1301696-45-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1301696-45-6(Hazardous Substances Data)

1301696-45-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1301696-45-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,0,1,6,9 and 6 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1301696-45:
(9*1)+(8*3)+(7*0)+(6*1)+(5*6)+(4*9)+(3*6)+(2*4)+(1*5)=136
136 % 10 = 6
So 1301696-45-6 is a valid CAS Registry Number.

1301696-45-6Relevant articles and documents

BZM055, an Iodinated Radiotracer Candidate for PET and SPECT Imaging of Myelin and FTY720 Brain Distribution

Briard, Emmanuelle,Orain, David,Beerli, Christian,Billich, Andreas,Streiff, Markus,Bigaud, Marc,Auberson, Yves P.

experimental part, p. 667 - 677 (2012/01/06)

FTY720 (fingolimod, Gilenya) is a sphingosine 1-phosphate (S1P) receptor modulator that shows significant therapeutic efficacy after oral administration to patients of multiple sclerosis. Because FTY720 does not contain any atom whose PET or SPECT radioisotope would have a half-life compatible with its pharmacokinetic properties, it cannot be used directly for imaging. Instead, we propose BZM055 as a surrogate tracer to study its pharmacokinetics and organ distribution in patients and, given that FTY720 accumulates in myelin sheaths, for myelin imaging. BZM055 (2a, 2-iodo-FTY720) can be easily radiolabeled with 123I (for SPECT) or 124I (for PET). Not only does it closely mimic the pharmacokinetics and organ distribution of FTY720, but also its affinity, selectivity for S1P receptors, phosphorylation kinetics, and overall physicochemical properties. [123I]BZM055 is currently under development for clinical imaging.

FTY720 HALOGENATED DERIVATIVES

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Page/Page column 39-40, (2011/06/26)

There is provided new iodo- or bromo-compounds and their use as diagnostic agents and imaging agents for diseases or disorders where S1P receptor expression is altered.

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