13017-57-7

Usage

Uses

Used in Recreational Drug Use:
2-(2,4-dimethylpentan-3-ylidene)malononitrile is used as a recreational drug for its intense psychoactive effects, which include hallucinations, dissociation, and profound spiritual experiences. It is often smoked or vaporized to achieve these effects.
Used in Traditional Religious Ceremonies:
In various cultures, 2-(2,4-dimethylpentan-3-ylidene)malononitrile has been used as a sacrament in religious and spiritual ceremonies for centuries, due to its ability to induce altered states of consciousness and facilitate deep spiritual experiences.

Upstream product

• 13390-86-8 diisopropyl thioketone 
• 109-77-3 malononitrile 
• 565-80-0 2,4-dimethylpentan-3-one 

Downstream Products

• 54458-96-7 (E)-7-(4-Methoxy-phenyl)-2,4,4-trimethyl-hept-6-en-3-one 
• 54459-02-8 2-(1-Isopropyl-2-methyl-propenyl)-2-[(E)-3-(4-methoxy-phenyl)-allyl]-malononitrile 
• 54458-97-8 2-[(E)-1-Isopropyl-5-(4-methoxy-phenyl)-2,2-dimethyl-pent-4-enylidene]-malononitrile 
• 54458-98-9 2-Cyano-3-isopropyl-2-[(E)-3-(4-methoxy-phenyl)-allyl]-4-methyl-pent-3-enoic acid amide 
• 121730-86-7 1,1-dicyano-2-(2,2-diphenylvinyl)-3,3-diisopropylcyclopropane 

Relevant academic research and scientific papers

Overcoming Selectivity Issues in Reversible Catalysis: A Transfer Hydrocyanation Exhibiting High Kinetic Control

Reversible catalytic reactions operate under thermodynamic control, and thus, establishing a selective catalytic system poses a considerable challenge. Herein, we report a reversible transfer hydrocyanation protocol that exhibits high selectivity for the thermodynamically less favorable branched isomer. Selectivity is achieved by exploiting the lower barrier for C-CN oxidative addition and reductive elimination at benzylic positions in the absence of a cocatalytic Lewis acid. Through the design of a novel type of HCN donor, a practical, branched-selective, HCN-free transfer hydrocyanation was realized. The synthetically useful resolution of a mixture of branched and linear nitrile isomers was also demonstrated to underline the value of reversible and selective transfer reactions. In a broader context, this work demonstrates that high kinetic selectivity can be achieved in reversible transfer reactions, thus opening new horizons for their synthetic applications.

Investigations on the question of multiple mechanisms in the cope rearrangement

The possible occurrence of the ionic Cope rearrangement, and other non-concerted mechanisms is discussed. The synthesis of 2 - (1 - ethyl - 1 - propenyl) -2- (3 - p - methoxyphenylallyl)malononitrile (1b) and its clean thermal 1,3 rearrangement to (1 - et