1301701-48-3Relevant academic research and scientific papers
Antineoplastic agents. 590. X-ray crystal structure of dolastatin 16 and syntheses of the dolamethylleuine and dolaphenvaline units
Pettit, George R.,Smith, Thomas H.,Xu, Jun-Ping,Herald, Delbert L.,Flahive, Erik J.,Anderson, Collin R.,Belcher, Paul E.,Knight, John C.
scheme or table, p. 1003 - 1008 (2011/07/29)
Three advances necessary to bring dolastatin 16 (1) into full-scale preclinical development as an anticancer drug have been accomplished. The X-ray crystal structure of dolastatin 16 has been solved, which allowed stereoselective syntheses of its two new
