130185-02-3Relevant academic research and scientific papers
Synthesis of isotopically chiral [13C]penciclovir (BRL 39123) and its use to determine the absolute configuration of penciclovir triphosphate formed in herpes virus infected cells
Jarvest,Barnes,Earnshaw,O'Toole,Sime,Hodge
, p. 555 - 556 (2007/10/02)
Isotopically chiral [13C]penciclovir (BRL 39123) has been synthesised via a stereospecific hydrolysis catalysed by the lipase from Candida cylindraceae and has been used to determine, by 13C NMR, that the triphosphate of penciclovir formed in herpes simplex type 1 infected cells has (S) stereochemistry with an enantiomeric purity of > 95%.
