130199-70-1

Basic information

• Product Name: 5-(3-Hydroxy-1-methylene-propyl)-2-methyl-cyclohexanone
• Synonyms: 5-(3-Hydroxy-1-methylene-propyl)-2-methyl-cyclohexanone
• CAS NO: 130199-70-1
• Molecular Weight: 182.263
• Mol File: 130199-70-1.mol

Chemical Properties

• CAS DataBase Reference: 5-(3-Hydroxy-1-methylene-propyl)-2-methyl-cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-Hydroxy-1-methylene-propyl)-2-methyl-cyclohexanone(130199-70-1)
• EPA Substance Registry System: 5-(3-Hydroxy-1-methylene-propyl)-2-methyl-cyclohexanone(130199-70-1)

Safety Data

• Hazardous Substances Data: 130199-70-1(Hazardous Substances Data)

Upstream product

• 3792-53-8 2-methyl-5-(prop-1-en-2-yl)cyclohexanone 
• 110-88-3 1,3,5-Trioxan 

Relevant articles and documents

Stabilization of reactive aldehydes by complexation with methylaluminum bis(2,6-diphenylphenoxide) and their synthetic application

Reactive aldehydes such as formaldehyde and α-chloro aldehydes can be successfully generated by treatment of readily available trioxane and α-chloro aldehyde trimers, respectively, with methylaluminum bis(2,6-diphenylphenoxide) (MAPH), and stabilized as their 1:1 coordination complexes with MAPH. The resulting CH2=O·MAPH complex reacts with a variety of olefins to furnish ene-reaction products with excellent regio- and stereoselectivities. In addition, this complex as well as α-chloro aldehyde-M APH complexes can be utilized as a stable source of gaseous formaldehyde and reactive α-chloro aldehydes, respectively, for the nucleophilic addition of various carbanions (organometallics, enolates, etc.). Formation of reactive aldehyde-MAPH complexes is firmly confirmed by 1H NMR spectroscopy. A space-filling model of aldehyde-M APH complexes implies that formaldehyde and α-chloro aldehydes coordinated with MAPH may be electronically stabilized by two parallel phenyl groups of aluminum ligands.