130231-96-8

Basic information

• Product Name: (2S,3S)-4,4-Dimethyl-2-(4-nitro-phenyl)-5-oxo-1-(toluene-4-sulfonyl)-pyrrolidine-3-carboxylic acid ethyl ester
• CAS NO: 130231-96-8
• Molecular Weight: 460.508
• Mol File: 130231-96-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S)-4,4-Dimethyl-2-(4-nitro-phenyl)-5-oxo-1-(toluene-4-sulfonyl)-pyrrolidine-3-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-4,4-Dimethyl-2-(4-nitro-phenyl)-5-oxo-1-(toluene-4-sulfonyl)-pyrrolidine-3-carboxylic acid ethyl ester(130231-96-8)
• EPA Substance Registry System: (2S,3S)-4,4-Dimethyl-2-(4-nitro-phenyl)-5-oxo-1-(toluene-4-sulfonyl)-pyrrolidine-3-carboxylic acid ethyl ester(130231-96-8)

Safety Data

• Hazardous Substances Data: 130231-96-8(Hazardous Substances Data)

Upstream product

• 13707-46-5 N-tosyl-4-nitrobenzaldimine 
• 30451-78-6 ethyl 2,2-dimethoxy-3,3-dimethylcyclopropanecarboxylate 

Relevant articles and documents

Highly Diastereoselective Synthesis of cis-3,4-Disubstituted γ-Lactams by the Reaction of Ethyl-2,2-Dialkoxycyclopropanecarboxylates with N-Tosyl Aldimines

In the presence of titanium(IV) chloride, ethyl 2,2-dialkoxycyclopropanecarboxylates reacted with imines to give γ-lactams.Especially, when N-tosyl aldimines were employed, cis-3,4-disubstituted γ-lactams were obtained in good yields with high diastereoselectivity.