130240-58-3

Upstream product

• 18658-65-6 N-tret-butoxycarbonyl-L-leucinyl-L-tyrosine methyl ester 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 448236-11-1 Boc-L-Leu-L-Tyr-OBzl 

Downstream Products

• 448236-12-2 N-{N-[N-(tert-butoxycarbonyl)-L-leucyl-L-tyrosyl]-L-phenylalanyl}-2-(phenylthio)pyrrolidin-3-one 

Relevant academic research and scientific papers

Synthesis, antimicrobial and anthelmintic activity of 2-amino-4-phenylthiazole derivatives of amino acids and peptides

A novel series of 2-amino-4-phenylthiazole derivatives of amino acids and peptides were synthesized by solution phase technique. The synthesized compounds were characterized by FTIR, 1H NMR and mass spectral analysis and evaluated for their antibacterial, antifungal and anthelmintic activities. The compounds exhibited significant antifungal and anthelmintic activities as compared to standard drugs fluconazole and mebendazole, respectively.

Parallel synthesis of new phenylalanino-2-(phenylthio)pyrrolidin-3-one scaffold-based analogues

Based on the specific PhePro proteolytic cleavage of the HIV-protease, we synthesized short pseudopeptides incorporating a 2-(phenylthio)pyrrolidin-3-one ring. We previously described various analogues based on this scaffold. We report herein a parallel m