130259-96-0

Basic information

• Product Name: N-(1-ethyl-3-piperidinyl)-2-methoxy-5-(N-(4-toluenesulfonyl)-amino)benzamide
• Synonyms: N-(1-ethyl-3-piperidinyl)-2-methoxy-5-(N-(4-toluenesulfonyl)-amino)benzamide
• CAS NO: 130259-96-0
• Molecular Weight: 431.556
• Mol File: 130259-96-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(1-ethyl-3-piperidinyl)-2-methoxy-5-(N-(4-toluenesulfonyl)-amino)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-ethyl-3-piperidinyl)-2-methoxy-5-(N-(4-toluenesulfonyl)-amino)benzamide(130259-96-0)
• EPA Substance Registry System: N-(1-ethyl-3-piperidinyl)-2-methoxy-5-(N-(4-toluenesulfonyl)-amino)benzamide(130259-96-0)

Safety Data

• Hazardous Substances Data: 130259-96-0(Hazardous Substances Data)

Upstream product

• 130259-92-6 5-Amino-N-(1-ethyl-piperidin-3-yl)-2-methoxy-benzamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 6789-94-2 1-ethylpiperidin-3-amine 
• 90763-46-5 2-methoxy-5-nitrobenzoyl chloride 
• 4840-67-9 N-(1-Ethyl-piperidin-3-yl)-2-methoxy-5-nitro-benzamide 

Downstream Products

• 130260-02-5 N-(1-ethyl-3-piperidinyl)-2-methoxy-5-(methylamino)benzamide 
• 130260-00-3 N-(1-ethyl-3-piperidinyl)-2-methoxy-5-(N-methyl-N-(4-toluenesulfonyl)amino)benzamide 

Relevant articles and documents

POTENTIAL NEUROLEPTICS OF THE ORTHOPRAMIDE SERIES; SYNTHESIS OF HETEROCYCLIC 5-AMINO-2-METHOXYBENZAMIDES AND OF SOME RELATED COMPOUNDS

2-Methoxy-5-nitrobenzoyl chloride was reacted with 2-(aminoethyl)-1-ethylpyrrolidine, 3-amino-1-ethylpiperidine, 4-amino-1-benzylpiperidine, 1-benzylpiperazine, and 1-amino-4-benzylpiperazine and gave the N-substituted 2-methoxy-5-nitrobenzamides VIa-VIe.Their reduction with hydrazine hydrate and Raney nickel in ethanol afforded the corresponding 5-amino-2-methoxybenzamides VIIa-VIIe.The amino amides VIIb and VIIc were transformed to methylamino compounds XIb and XIc via the 4-toluenesulfonamides VIIIb and VIIIc and the N-methyl-4-toluenesulfonamides Xb and Xc.The N-(1-benzyl-4-piperidinyl)amides VIc, VIIc, and XIc were found to be mild neuroleptics having antiapomorphine, some cataleptic and some ataxic activity.