130267-72-0Relevant academic research and scientific papers
Synthesis of 2,3,5-Substituted 1H-Pyrroles by a Cp2TiCl2-catalyzed Multicomponent Reaction of Terminal Alkynes with Nitriles and EtAlCl2
Dzhemilev, U. M.,Khafizova, L. O.,Richter, N. A.,Shaibakova, M. G.
, p. 218 - 224 (2020)
Abstract: A one-pot synthesis of 2,3,5-substituted 1H-pyrroles with yields of 37–77% by the reaction of terminal alkynes with aromatic and heteroaromatic nitriles in the presence of EtAlCl2 and the Cp2TiCl2 catalyst has been developed. Spectral-luminescent properties were studied and intense photoluminescence of 2,3,5-triphenyl-1H-pyrrole, 3-(2-phenylethyl)-2,5-diphenyl-1H-pyrrole, and 2,5-diphenyl-3-(pyridin-2-yl)-1H-pyrrole had been detected.
Organische Synthesen mit Uebergangsmetall-Komplexen XLV. 3-Hydroxypyridine, 1H-Pyrrole und 2-Hydroxypyrrol-Derivate aus einem Aminocarben-Chromkomplex und Alkinen
Aumann, Rudolf,Heinen, Heinrich
, p. C1 - C6 (2007/10/02)
Pyrroles VI, 3-hydroxypyridines V and 2-hydroxypyrroles IX have been obtained from (amino,phenylcarbene)pentacarbonyl-chromium (I) by simple two-step procedures.The first step involves the generation of 2-azaallenyl(pentacarbonyl)chromium complexes III, and VIII by condensation of I with an aldehyde II and an acid chloride VII, respectively.Complexes III react with alkynes IVa-i to give pyrroles VI and 3-hydroxypyridines V.VIII adds alkynes IVa,e,g to give 2-hydroxypyrroles IX.
