130291-45-1

Upstream product

• 96013-55-7 1-[(4-methylphenyl)sulfonyl]-5,6-dihydro-1H-piperidin-2-one 
• 74-88-4 methyl iodide 
• 1026230-55-6 3-Methyl-3-phenylsulfanyl-1-(toluene-4-sulfonyl)-piperidin-2-one 
• 23438-61-1 1-(toluene-4-sulfonyl)piperidin-2-one 
• 143076-20-4 N-(p-Toluenesulfonyl)-3-(phenylthio)-2-piperidone 
• 201230-82-2 carbon monoxide 
• 211814-64-1 5-[N-(4-methylphenylsulfonyl)amino]penta-1,2-diene 

Downstream Products

• 143076-11-3 8a-Methyl-2-(p-toluenesulfonyl)-cis-1,2,3,4,4a,5,6,8a-octahydro-1,6-dioxoisoquinoline 

Relevant academic research and scientific papers

Ru-catalyzed cyclocarbonylation of α-and β-allenic sulfonamides: Synthesis of γ- and δ-unsaturated lactams

(equation presented) The Ru-catalyzed cyclocarbonylation of α-or β-allenic sulfonamides in the presence of Ru3(CO)12 (1 mol %) and Et3N (1.5 equiv) under CO atmosphere (20 atm) in dioxane at 100°C for 9 h gave heterocyclic

Morita-Baylis-Hillman reaction of lactams and lactones with alkyl halides and epoxides catalyzed by hydroxysulfides

A new Morita-Baylis-Hillman reaction methodology in which alkyl halides and epoxides act as electrophiles in their reaction with lactones and lactams is shown. Catalysis is efficiently performed by hydroxy sulfides under basic conditions. The procedure works efficiently with many alkyl halides but fails with aldehydes with which a conventional acid-catalyzed procedure is used.