130296-12-7

Upstream product

• 130277-18-8 (2S,3R,4E)-2-azido-3-O-benzoyl-1-O-(p-tolylsulfonyl)-4-octadecene-1,3-diol 
• 130296-11-6 (2R,3R,4E)-1-Acetylthio-2-azido-3-benzoyloxy-4-octadecene 

Relevant academic research and scientific papers

Synthesis of β-Lactosyl 1-Thioceramide

3-O-Benzoyl-azidosphingosine 3 was transformed into the corresponding 1-thio derivative 6.Its sodium sulfide salt 6A was treated with hepta-O-acetyl-α-lactosyl bromide 8 to provide after complete O-deprotection the β-connected thioglycoside 9.Azido group reduction and N-palmitoylation led to the desired β-lactosyl thioceramide 1; for structural assignments it was converted into the per-O-acetyl derivative 2.