13030-09-6

Basic information

• Product Name: L-Glutamic acid alpha-benzyl ester
• Synonyms: A-BENZYL-L-GLUTAMATE;L-GLUTAMIC ACID ALPHA-BENZYL ESTER;L-ALPHA-BENZYL GLUTAMATE;H-GLU-OBZL;GLUTAMIC ACID-OBZL;1-benzyl l-glutamate;l-glutamic acid 1-benzyl ester;H-L-Glu-OBzl
• CAS NO: 13030-09-6
• Molecular Formula: C₁₂H₁₅NO₄
• Molecular Weight: 237.25
• Product Categories: Amino Acid Derivatives;Amino Acids;Glutamic acid [Glu, E];Amino Acids and Derivatives;Amino Acid Benzyl Esters;Amino Acids (C-Protected);Biochemistry;Amino Acid Derivatives
• Mol File: 13030-09-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 157 °C
• Boiling Point: 416 °C at 760 mmHg
• Flash Point: 205.4 °C
• Appearance: /
• Density: 1.245 g/cm³
• Vapor Pressure: 1.15E-07mmHg at 25°C
• Refractive Index: 1.555
• Storage Temp.: -15°C
• PKA: 4.21±0.10(Predicted)
• CAS DataBase Reference: L-Glutamic acid alpha-benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Glutamic acid alpha-benzyl ester(13030-09-6)
• EPA Substance Registry System: L-Glutamic acid alpha-benzyl ester(13030-09-6)

Safety Data

• Hazardous Substances Data: 13030-09-6(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C12H15NO4/c13-10(6-7-11(14)15)12(16)17-8-9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,14,15)/t10-/m0/s1

Upstream product

• 56-86-0 L-glutamic acid 
• 100-51-6 benzyl alcohol 
• 30924-93-7 Boc-Glu-OBn 
• 73469-43-9 dibenzyl N-trityl-(S)-glutamate 
• 73488-68-3 Tr-L-Glu(OBzl)-OH 
• 3705-42-8 Cbz-(L)-Glu-OBn 
• 2768-50-5 dibenzyl L-glutamate 

Downstream Products

• 62188-74-3 H-Glu(O-t-Bu)-OBzl 
• 30924-93-7 Boc-Glu-OBn 
• 89106-05-8 2-{4-[(2,4-diamino-6-pteridinylmethyl)methylamino]benzoylamino}pentanedioic acid 1-benzyl ester 
• 949588-04-9 benzylhexadecandioyl-L-Glu-OBn 
• 82153-39-7 Ophthalmic acid 
• 89106-07-0 N^α-(tert-Butyloxycarbonyl)-N^ε-10-methylpteroyl)-γ-L-glutamyl>-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysine Benzyl (O^α-glu) 2-(Trimethylsilyl)ethyl (O^lys) Ester 
• 89106-08-1 N^α-(tert-Butyloxycarbonyl)-N^ε-10-methylpteroyl)-L-γ-glutamyl>-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysyl-N^ε-(benzyloxycarbonyl)-L-lysine Benzyl (O^α-glu) Ester 
• 79974-10-0 N-methylamino>benzoyl>-L-γ-glutamyl>-L-glutamic acid tribenzyl ester 
• 79974-09-7 (S)-2-{(S)-4-Benzyloxycarbonyl-4-[4-(benzyloxycarbonyl-methyl-amino)-benzoylamino]-butyrylamino}-succinic acid dibenzyl ester 
• 79974-08-6 (S)-2-[4-(Benzyloxycarbonyl-methyl-amino)-benzoylamino]-4-(benzyloxycarbonylmethyl-carbamoyl)-butyric acid benzyl ester 
• 41600-13-9 N-methylamino>benzoyl>-L-γ-glutamyl>-L-glutamic acid 
• 64801-58-7 methotrexate-γ-aspartate 
• 79974-07-5 (S)-4-Benzylcarbamoyl-2-[4-(benzyloxycarbonyl-methyl-amino)-benzoylamino]-butyric acid benzyl ester 
• 79974-06-4 (S)-2-[4-(Benzyloxycarbonyl-methyl-amino)-benzoylamino]-4-pentylcarbamoyl-butyric acid benzyl ester 

Relevant articles and documents

High selective autocatalytic esterification of glutamic acid by benzyl alcohol with CuCl2 promoting

We found that the esterification of l-glutamic acid by benzyl alcohol is greatly promoted by CuCl2 even in H2O solvent, and the selectivity and yield of γ-benzyl ester of l-glutamic acid achieved 100% and 95.31%. Metal cation coordin

SMALL MOLECULE VE-PTP INHIBITORS

The present disclosure relates to compounds capable of inhibiting vascular endothelial protein tyrosine phosphatase (VE-PTP). These compounds are also capable of activating Tie2 receptor-mediated signaling. The present disclosure also relates to pharmaceutically acceptable salts of said compounds, to pharmaceutical compositions comprising such compounds and/or pharmaceutically acceptable salts thereof, and to the use of such compounds, pharmaceutically acceptable salts thereof, and/or pharmaceutical compositions comprising the same in treating diseases and/or conditions mediated by VE-PTP signaling, such as those mediated by Angiopoietm/Tie2 signaling.