130336-41-3Relevant academic research and scientific papers
CONVENIENT ENANTIOSELECTIVE HYDROLYSIS OF RACEMIC trans-1-ACETOXY-2-ARYLOXYCYCLOHEXANES BY CRUDE PIG LIVER ACETONE POWDER (PLAP)
Basavaiah, D.,Krishna, P. Rama,Bharathi, T. K.
, p. 4347 - 4348 (1990)
Crude pig liver acetone powder (PLAP) hydrolyzes trans-1-acetoxy-2-aryloxycyclohexanes enantioselectively to produce the corresponding alcohols in high optical purities.
A Convenient Enantioselective Synthesis of trans-2-Aryloxycyclohexan-1-ols Using Pig Liver Acetone Powder (PLAP) as Biocatalyst
Basavaiah, Deevi,Krishna, Peddinti Rama,Bharathi, Tirumala K.
, p. 439 - 454 (2007/10/02)
Pig liver acetone powder (PLAP) has been used as a biocatalyst for enantioselective hydrolysis of racemic trans-1-acetoxy-2-aryloxycyclohexanes to produce the resulting (R,R)-2-aryloxycyclohexan-1-ols upto >99percent enantiomeric purities. (R,R)-Selectivity in this hydrolysis of racemic trans-2-aryloxycyclohexyl acetates was explained on the basis of Jones' three dimensional active site-model.
