130339-48-9Relevant academic research and scientific papers
Synthesis of benzylaminopyrimidines and their fungicidal activities against wheat brown rust and barley powdery mildew
Yamanaka,Moritomo,Fujii,Tanaka,Fukuda,Nishimura
, p. 223 - 229 (1998)
Members of a new class of fungicide containing benzyl-aminopyrimidine as a core structure were synthesized and their fungicidal potencies against wheat brown rust, Puccinia recondita, and barley powdery mildew, Erysiphe graminis, were assessed. Among these fungicides, N-(fluoroalkoxy or fluorophenoxybenzyl)-4-pyrimidinamines showed notable preventive activities. The potency of the new pyrimidines was increased when a difluoromethoxy or tetrafluorophenoxy group was introduced at the 4- or 3-position of the phenyl moiety and a methyl or ethyl group was introduced at the benzyl position. Structure-activity relationships are discussed.
