1303439-10-2

Upstream product

• 6298-19-7 2-chloro-3-aminopyridine 
• 1303439-09-9 (E)-1-benzyl-5-chloro-7-(pent-1-enyl)pyrido[4,3-b]pyrazine-2,3(1H,4H)-dione 
• 1303439-03-3 1-benzyl-7-bromo-5-chloropyrido[3,4-b]pyrazine-2,3(1H,4H)-dione 
• 1303439-02-2 N₁-benzyl-N₂-(4,6-dibromo-2-chloropyridin-3-yl)oxalamide 
• 887570-91-4 4,6-dibromo-2-chloropyridin-3-amine 

Downstream Products

• 1303439-08-8 5-amino-1-benzyl-7-pentylpyrido[4,3-b]pyrazine-2,3(1H,4H)-dione 

Relevant academic research and scientific papers

COMPOUNDS AND COMPOSITIONS AS TLR-7 ACTIVITY MODULATORS

The invention provides compounds, immunogenic compositions and pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors 7. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine.