1303532-75-3Relevant academic research and scientific papers
Transition-Metal-Free Selective Oxidative C(sp3)-S/Se Coupling of Oxindoles, Tetralone, and Arylacetamides: Synthesis of Unsymmetrical Organochalcogenides
Prasad, Ch. Durga,Sattar, Moh.,Kumar, Sangit
, p. 774 - 777 (2017)
Transition-metal-free synthetic methods have been developed for the preparation of unsymmetrical diaryl and aryl alkyl chalcogenides: sulfones, sulfides, and selenides from the sp3-C-H bond of oxindole, tetralone, arylacetamide, and aryl chalco
Iron-Catalyzed Cross-Dehydrogenative Coupling of Oxindoles with Thiols/Selenols for Direct C(sp3)?S/Se Bond Formation
Huang, Lu-Shan,Han, Dong-Yang,Xu, Da-Zhen
supporting information, p. 4016 - 4021 (2019/07/18)
The C?X (S/Se) bonds are common and ubiquitous in natural products and pharmaceuticals. Here, we report an iron-catalyzed cross-dehydrogenative coupling (CDC) reaction for the direct synthesis of C(sp3)?X (S/Se) bonds from oxindoles, phenylacetamides, pyrazolones, phenylacetonitriles and ethyl cyanoacetate with thiols and selenols. All the reactions were performed under simple and mild conditions, and air (molecular oxygen) was employed as an ideal green oxidant, thus promising broad application in chemical industry and modification of bioactive molecules. (Figure presented.).
