1303541-49-2

Upstream product

• 134209-90-8 1,7,8-triaza-3,3,6,6-tetramethyl-5-oxa-2-oxo-1-phenylspiro<3,4>oct-7-ene 
• 250645-59-1 3,6-bis-(4-(trifluoromethyl)phenyl)-1,2,4,5-tetrazine 

Relevant academic research and scientific papers

Interaction of β-lactam carbenes with 3,6-diphenyltetrazines: A five-step cascade reaction for the direct construction of indeno[2,1-b]pyrrol-2- ones

A study of the nucleophilic addition of β-lactam carbenes to 3,6-diphenyltetrazines is reported. Instead of the formation of pyrazole derivatives like most reactions between nucleophilic or ambiphilic carbenes and 3,6-disubstituted tetrazines, β-lactam carbenes reacted with 3,6-diphenyltetrazines to produce indeno[2,1-b]pyrrol-2-ones in good yields. The reaction proceeds most probably through a five-step cascade process. This work has not only provided a one-pot operation for the efficient construction of mutisubstituted indeno[2,1-b]pyrrol-2-ones but also revealed the nucleophilicity of β-lactam carbenes.