1303588-25-1

Basic information

• Product Name: 1-Methyl-6-(3-(trifluoroMethyl)phenyl)-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-one
• Synonyms: 1-Methyl-6-(3-(trifluoroMethyl)phenyl)-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-one
• CAS NO: 1303588-25-1
• Molecular Formula: C₁₅H₁₂F₃N₃O
• Molecular Weight: 307.2704896
• Mol File: 1303588-25-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Methyl-6-(3-(trifluoroMethyl)phenyl)-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-6-(3-(trifluoroMethyl)phenyl)-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-one(1303588-25-1)
• EPA Substance Registry System: 1-Methyl-6-(3-(trifluoroMethyl)phenyl)-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-one(1303588-25-1)

Safety Data

• Hazardous Substances Data: 1303588-25-1(Hazardous Substances Data)

Usage

Chemical classification

Pyrido[2,3-b]pyrazin-2(1H)-one derivative
A compound derived from the parent structure of pyrido[2,3-b]pyrazin-2(1H)-one, with modifications to its chemical structure.

Methyl group

1-position
A CH3 functional group attached to the first position of the pyrido[2,3-b]pyrazin-2(1H)-one core structure.

3-(Trifluoromethyl)phenyl group

6-position
A phenyl ring with a CF3 (trifluoromethyl) group attached to the third position, located at the sixth position of the pyrido[2,3-b]pyrazin-2(1H)-one core structure.
5. Dihydropyrido ring system
A bicyclic ring structure consisting of a pyridine ring fused to a dihydro-pyrrole ring, which is part of the core structure of the compound.
6. Potential drug candidate
A compound with the possibility of being developed into a pharmaceutical drug due to its various pharmacological activities.

Pharmacological activities

Antitumor and antifungal properties
The compound exhibits potential antitumor (cancer cell growth inhibition) and antifungal (inhibition of fungal growth) activities.

Applications

Medicinal chemistry research and drug development
The compound may be used in the field of medicinal chemistry for research purposes and as a starting point for the development of new drugs.

Further studies needed

Biological and chemical properties
Additional research is required to fully understand the compound's biological and chemical properties, which will help determine its potential as a drug candidate.

Upstream product

• 1303588-23-9 ethyl 2-(3-nitro-6-(3-(trifluoromethyl)phenyl)pyridin-2-ylamino)acetate 
• 1303588-22-8 ethyl 2-(3-nitro-6-(3-(trifluoromethyl)phenyl)pyridin-2-ylamino)acetate 
• 16013-85-7 2,6-dicholoro-3-nitropyridine 
• 73895-79-1 N-(6-chloro-3-nitro-2-pyridinyl)glycine ethyl ester 
• 1303588-24-0 6-(3-(trifluoromethyl)phenyl)-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-one 
• 74-88-4 methyl iodide 

Downstream Products

• 1303588-26-2 1-methyl-6-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine 

Relevant articles and documents

BICYCLIC PYRIDINES AND ANALOGS AS SIRTUIN MODULATORS

Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.