1303609-75-7Relevant academic research and scientific papers
Novel palladium-free synthesis of a key quinazolinap precursor
Milhau, Ludovic,Guiry, Patrick J.
supporting information; experimental part, p. 383 - 385 (2011/04/22)
A novel, short synthetic route has been successfully developed for a key precursor of Quinazolinap ligands. The key step is a Friedel-Crafts-type reaction between 2-naphthol and 4-chloroquinazoline, with moderate to quantitative yields recorded. A variation of this reaction allows for the introduction of an amine group on the naphthalene unit. Georg Thieme Verlag Stuttgart New York.
