130362-13-9

Upstream product

• 17199-29-0 (S)-Mandelic acid 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 130464-46-9 (1S,2S,3R,4R)-2-<(S)-Mandeloxycarbonyl>bicyclo<2.2.1>heptane-3-carboxylic Acid 
• 1192881-59-6 bis((S)-2-(4-methoxybenzyloxy)-2-oxo-1-phenylethyl) 5-nitroisophthalate 
• 1192881-54-1 bis((S)-2-(4-methoxybenzyloxy)-2-oxo-1-phenylethyl) 3-nitrophthalate 
• 1192881-58-5 bis((S)-2-(4-methoxybenzyloxy)-2-oxo-1-phenylethyl) terephthalate 
• 1192881-56-3 (S)-2-(4-methoxybenzyloxy)-2-oxo-1-phenylethyl 3,5-dinitrobenzoate 
• 130362-18-4 (1S,2R,3S,4R)-2-<(R)-Mandeloxycarbonyl>bicyclo<2.2.1>hept-5-ene-3-carboxylic Acid 
• 132674-12-5 (1S,2R,3S,4R)-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid mono-[(R)-(4-methoxy-benzyloxycarbonyl)-phenyl-methyl] ester 
• 132747-50-3 (1R,2S,3R,4S)-Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid mono-[(R)-(4-methoxy-benzyloxycarbonyl)-phenyl-methyl] ester 

Relevant academic research and scientific papers

A novel chiral resolving reagent, bis((s)-mandelic acid)-3-nitrophthalate, for amlodipine racemate resolution: Scalable synthesis and resolution process

A novel bis((S)-mandelic acid)-3-nitrophthalate (1), a chiral resolving reagent for the separation of (S)-(-)-isomers of amlodipine from the racemate thereof, is designed and synthesized. A simple three-step pilot-scale preparation of 1, along with the optimization of a resolution process on the racemate amlodipine, is reported.