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3-(Boc-amino)cyclobutanemethanol, also known as Boc-amino-cyclobutanemethanol, is a chemical compound that features a cyclobutane ring with an amino group and a Boc (tert-butoxycarbonyl) protecting group attached to one of the carbon atoms, along with a hydroxyl group on another carbon atom. 3-(Boc-aMino)cyclobutaneMethanol is widely recognized for its role as a building block in organic synthesis, particularly for the preparation of complex molecules in the pharmaceutical and agrochemical industries. The presence of the Boc protecting group allows for the controlled deprotection of the amino group under acidic conditions, facilitating further chemical reactions and the development of diverse chemical compounds.

130369-05-0

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130369-05-0 Usage

Uses

Used in Pharmaceutical Industry:
3-(Boc-amino)cyclobutanemethanol is utilized as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and the presence of the Boc protecting group make it an ideal candidate for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 3-(Boc-amino)cyclobutanemethanol serves as a vital component in the creation of complex molecules with pesticidal properties. Its ability to be easily modified and incorporated into larger structures allows for the design of novel agrochemicals with improved efficacy and selectivity.
Used in Drug Discovery:
3-(Boc-amino)cyclobutanemethanol is employed as a valuable tool in drug discovery, where its reactivity and structural features contribute to the development of new chemical entities with potential therapeutic benefits. The Boc protecting group enables selective reactions and the synthesis of diverse chemical libraries for screening and optimization.
Used in Material Science:
In the field of material science, 3-(Boc-amino)cyclobutanemethanol is used for the synthesis of advanced materials with unique properties. Its ability to form complex structures and participate in various chemical reactions makes it a promising candidate for the development of new materials with applications in various industries, such as electronics, coatings, and adhesives.

Check Digit Verification of cas no

The CAS Registry Mumber 130369-05-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,3,6 and 9 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 130369-05:
(8*1)+(7*3)+(6*0)+(5*3)+(4*6)+(3*9)+(2*0)+(1*5)=100
100 % 10 = 0
So 130369-05-0 is a valid CAS Registry Number.

130369-05-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl N-[3-(hydroxymethyl)cyclobutyl]carbamate

1.2 Other means of identification

Product number -
Other names Pyrazolidine-1,2-dicarboxylic acid 1-benzyl ester 2-tert-butyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:130369-05-0 SDS

130369-05-0Downstream Products

130369-05-0Relevant academic research and scientific papers

Radical hydroxymethylation of alkyl iodides using formaldehyde as a C1 synthon

Caiger, Lewis,Constantin, Timothée,Douglas, James J.,Juliá, Fabio,Leonori, Daniele,Sheikh, Nadeem S.,Sinton, Conar

, p. 10448 - 10454 (2021/08/20)

Radical hydroxymethylation using formaldehyde as a C1 synthon is challenging due to the reversible and endothermic nature of the addition process. Here we report a strategy that couples alkyl iodide building blocks with formaldehyde through the use of photocatalysis and a phosphine additive. Halogen-atom transfer (XAT) from α-aminoalkyl radicals is leveraged to convert the iodide into the corresponding open-shell species, while its following addition to formaldehyde is rendered irreversible by trapping the transient O-radical with PPh3. This event delivers a phosphoranyl radical that re-generates the alkyl radical and provides the hydroxymethylated product.

?-LACTAMASE INHIBITOR AND USE THEREOF

-

Paragraph 0217; 0218, (2020/12/10)

Provided are a β-lactamase inhibitor of formula (I), or an ester, a stereoisomer or a pharmaceutically acceptable salt thereof, and a method of preparing the same. Further provided is a pharmaceutical composition comprising the β-lactamase inhibitor of formula (I), or the ester, the stereoisomer or pharmaceutically acceptable salt thereof. In addition, the present invention relates to a method for treating diseases caused by bacterial infection, which comprises administering the β-lactamase inhibitor of formula (I), or the ester, the stereoisomer or the pharmaceutically acceptable salt thereof to a patient or a subject in need.

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