1303963-54-3Relevant academic research and scientific papers
Enantioselective direct aldol reactions of achiral ketones with racemic enolizable α-substituted aldehydes: Scope and limitations
Ward, Dale E.,Jheengut, Vishal,Beye, Garrison E.,Gillis, H. Martin,Karagiannis, Athanasios,Becerril-Jimenez, Fabiola
, p. 508 - 512 (2011/04/24)
Aldol reactions of racemic enolizable dioxolan-protected α-substituted-β-ketoaldehydes with representative achiral ketones catalyzed by proline or 5-(2-pyrrolidine-2-yl)-1H-tetrazole in wet DMSO proceed with dynamic kinetic resolution (or via DYKAT with an α-substituted- β-alkoxyaldehyde) to give adducts with high dr and ee. Georg Thieme Verlag Stuttgart.
