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1303974-65-3

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1303974-65-3 Usage

General Description

1-(tert-butoxycarbonyl)-4,4-difluoropiperidine-3-carboxylic acid is a chemical compound with a complex structure that includes a piperidine ring and a carboxylic acid group. The presence of the tert-butoxycarbonyl group indicates that the compound is likely a protected amino acid derivative, often used in organic synthesis to protect and manipulate specific functional groups. The difluoro substitution on the piperidine ring indicates the presence of two fluorine atoms, which can alter the reactivity and properties of the compound. Overall, this compound likely has uses in organic synthesis, pharmaceutical research, and other chemical applications due to its unique structure and functional groups.

Check Digit Verification of cas no

The CAS Registry Mumber 1303974-65-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,0,3,9,7 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1303974-65:
(9*1)+(8*3)+(7*0)+(6*3)+(5*9)+(4*7)+(3*4)+(2*6)+(1*5)=153
153 % 10 = 3
So 1303974-65-3 is a valid CAS Registry Number.

1303974-65-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 4,4-difluoro-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-3-carboxylic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1303974-65-3 SDS

1303974-65-3Downstream Products

1303974-65-3Relevant articles and documents

Semi-Industrial Fluorination of β-Keto Esters with SF 4: Safety vs Efficacy

Bugera, Maksym Y.,Khairulin, Andrii R.,Kliukovskyi, Denys V.,Ryabukhin, Sergey V.,Semenov, Sergey V.,Shevchenko, Valerii O.,Tarasenko, Karen V.,Trofymchuk, Serhii A.,Volochnyuk, Dmitriy M.

, p. 565 - 574 (2020/03/27)

The possibility of deoxofluorination of β-keto esters using SF 4 was investigated. The scope and limitation of the reaction were determined. The efficient method for the synthesis of β,β-difluorocarboxylic acids was elaborated based on the reaction. The set of mentioned acids, being the perspective building blocks for medicinal chemistry, were synthesized on multigram scale. The safety of SF 4 use was discussed. The described method does not improve upon the safety of using SF 4, but practical recommendations for working with the reagent are proposed. Despite the hazards of using toxic SF 4, a significant increase of efficacy in the synthesis of medicinal-chemistry-relevant building blocks, based on the reaction, in comparison with earlier described approaches is shown.

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