130408-72-9Relevant academic research and scientific papers
Minor structural differences in Boc-CCK-4 derivatives dictate affinity and selectivity for CCK-A and CCK-B reeeptors
Shiosaki,Chun Wel Lin,Kopecka,Bianchi,Miller,Stashko,Witte
, p. 1169 - 1172 (2007/10/03)
We previously reported novel Boc-CCK-4 (Boc-Trp-Met-Asp-Phe-NH2) derivatives possessing the general structure Boc-Trp-Lys[Nε-CO-NH-(R-Ph)]- Asp-Phe-NH2 (Shiosaki et al. J. Med. Chem. 1991, 34, 2837-2842). In contrast to Boc-CCK-4, wh
Boc-CCK-4 derivatives containing side-chain ureas as potent and selective CCK-A receptor agonists
Shiosaki,Lin,Kopecka,Tufano,Bianchi,Miller,Witte,Nadzan
, p. 2837 - 2842 (2007/10/02)
Novel Boc-CCK-4 derivatives were communicated recently as having high potency and selectivity for the CCK-A receptor (Shiosaki et al. J. Med. Chem. 1990, 33, 2950-2952). While Boc-CCK-4 binds selectively to the CCK-B receptor, replacement of the methionin
