1304101-23-2Relevant academic research and scientific papers
Potent and selective phosphopeptide mimetic prodrugs targeted to the Src homology 2 (SH2) domain of signal transducer and activator of transcription 3
Mandal, Pijus K.,Gao, Fengqin,Lu, Zhen,Ren, Zhiyong,Ramesh, Rajagopal,Birtwistle, J. Sanderson,Kaluarachchi, Kumaralal K.,Chen, Xiaomin,Bast, Robert C.,Liao, Warren S.,McMurray, John S.
, p. 3549 - 3563 (2011/07/30)
Signal transducer and activator of transcription 3 (Stat3), a target for anticancer drug design, is activated by recruitment to phosphotyrosine residues on growth factor and cytokine receptors via its SH2 domain. We report here structure-activity relation
