13042-45-0

Basic information

• Product Name: 1,3-Dioxan-5-amine,2-phenyl-,trans-(9CI)
• Synonyms: 1,3-Dioxan-5-amine,2-phenyl-,trans-(9CI)
• CAS NO: 13042-45-0
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.22
• Product Categories: PHENYL
• Mol File: 13042-45-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Dioxan-5-amine,2-phenyl-,trans-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxan-5-amine,2-phenyl-,trans-(9CI)(13042-45-0)
• EPA Substance Registry System: 1,3-Dioxan-5-amine,2-phenyl-,trans-(9CI)(13042-45-0)

Safety Data

• Hazardous Substances Data: 13042-45-0(Hazardous Substances Data)

Usage

General Description

The chemical 1,3-Dioxan-5-amine,2-phenyl-,trans-(9CI) is an organic compound with the molecular formula C9H13NO. It is also known as trans-2-Phenyl-1,3-dioxan-5-amine and has a trans configuration. This chemical is a secondary amine, meaning it has two alkyl or aryl groups attached to the nitrogen atom. It is commonly used in the synthesis of pharmaceuticals and agrochemicals due to its versatile reactivity and ability to form various types of chemical bonds. It is important to handle this compound with caution and to follow safety protocols when working with it in a laboratory setting.

Upstream product

• 1125-88-8 benzaldehyde dimethyl acetal 
• 99504-58-2 cis-2-phenyl-5-nitro-1,3-dioxane 
• 943655-64-9 N-(trans-2-phenyl-1,3-dioxan-5-yl)phenylacetamide 
• 99504-57-1 trans-2-phenyl-5-nitro-1,3-dioxane 

Relevant articles and documents

Ammonium Chloride-Promoted Rapid Synthesis of Monosubstituted Ureas under Microwave Irradiation

Monosubstituted ureas are important scaffolds in organic chemistry. They appear in various biologically active compounds and serve as versatile precursors in synthesis. Monosubstituted ureas were originally prepared using toxic and hazardous phosgene equivalents. Modern methods include transamidation of urea and nucleophilic addition to cyanate salts, both of which suffer from a narrow substrate scope due to the need for a strong acid and prolonged reaction times. We hereby report that ammonium chloride can promote the reaction between amines and potassium cyanate to generate monosubstituted ureas in water. This method proceeds rapidly under microwave irradiation and tolerates a broad range of functional groups. Unlike previous strategies, it is compatible with other nucleophiles, acid-labile moieties, and most of the common protecting groups. The products precipitate out of solution, allowing facile isolation without column chromatography.

Synthesis and CB1 receptor activities of dimethylheptyl derivatives of 2-arachidonoyl glycerol (2-AG) and 2-arachidonyl glyceryl ether (2-AGE)

Results from a factor analysis and activity studies of commercially available endocannabinoid-type compounds set the starting point for the current study where dimethylheptyl (DMH) analogues of two endocannabinoids, 2-arachidonoyl glycerol (2-AG) and 2-ar