13044-18-3 Usage
General Description
The chemical 4-[1-ethyl-1-(4-hydroxy-3,5-dimethylphenyl)propyl]-2,6-dimethylphenol, also known as etodolac, is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to relieve pain and reduce inflammation in conditions such as osteoarthritis and rheumatoid arthritis. It works by inhibiting the production of prostaglandins, which are responsible for causing pain and inflammation in the body. Etodolac is a crystalline white powder with a molecular weight of 287.4 and is soluble in water and methanol. It is typically administered orally in the form of tablets or capsules and has a relatively long half-life in the body, allowing for once or twice daily dosing. Common side effects of etodolac include stomach upset, dizziness, and headache, and it can also increase the risk of serious cardiovascular events such as heart attack and stroke.
Check Digit Verification of cas no
The CAS Registry Mumber 13044-18-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,0,4 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 13044-18:
(7*1)+(6*3)+(5*0)+(4*4)+(3*4)+(2*1)+(1*8)=63
63 % 10 = 3
So 13044-18-3 is a valid CAS Registry Number.
InChI:InChI=1/C21H28O2/c1-7-21(8-2,17-9-13(3)19(22)14(4)10-17)18-11-15(5)20(23)16(6)12-18/h9-12,22-23H,7-8H2,1-6H3
13044-18-3Relevant articles and documents
Structure-activity relationships of bisphenol a analogs at estrogen receptors (ERs): Discovery of an ERα-selective antagonist
Maruyama, Keisuke,Nakamura, Masaharu,Tomoshige, Shusuke,Sugita, Kazuyuki,Makishima, Makoto,Hashimoto, Yuichi,Ishikawa, Minoru
, p. 4031 - 4036 (2013/07/19)
Our multi-template approach for drug discovery, focusing on protein targets with similar fold structures, has yielded lead compounds for various targets. We have also shown that a diphenylmethane skeleton can serve as a surrogate for a steroid skeleton. H
