13045-94-8 Usage
Uses
Used in Oncology:
4-[bis(2-chloroethyl)amino]-D-phenylalanine is used as a chemotherapy agent for the treatment of various cancers. Its primary application is in the management of blood and lymphatic system cancers due to its ability to alkylate and damage the DNA of cancer cells, thereby inhibiting their growth and proliferation.
4-[bis(2-chloroethyl)amino]-D-phenylalanine's most common side effects stem from its impact on bone marrow, which can lead to conditions such as anemia, neutropenia, and thrombocytopenia. Despite these potential toxicities, the anticancer properties of 4-[bis(2-chloroethyl)amino]-D-phenylalanine have established it as a crucial component in the chemotherapy regimen for specific cancer types.
Check Digit Verification of cas no
The CAS Registry Mumber 13045-94-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,0,4 and 5 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 13045-94:
(7*1)+(6*3)+(5*0)+(4*4)+(3*5)+(2*9)+(1*4)=78
78 % 10 = 8
So 13045-94-8 is a valid CAS Registry Number.
13045-94-8Relevant academic research and scientific papers
Process Of Making Optically Pure Melphalan
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Page/Page column 5, (2009/10/01)
This invention provides a process of making 4-(bis-(2-hydroxyethyl)amino)-L-phenylalanine of the formula by hydroxyethylation, in a regioselective manner, of the aromatic amino group rather than the glycinic amino group.
