130451-88-6Relevant academic research and scientific papers
MECHANISM OF DECARBALKOXYLATION OF ARYLMETHYLENE-PROPANEDIOIC ACID DIMETHYL ESTERS
Bernard, Angela M.,Cerioni, Giovanni,Piras, Pier Paolo
, p. 3929 - 3940 (2007/10/02)
The decarbalkoxylation in DMSO-NaX-H2O, of some arylmethylene propanedioic acid dimethyl esters is studied.Both the relative rates of the para (R = NO2, H, CH3, OCH3) and the ortho substituted aryl derivatives, together with the stereochemical outcome, support a preliminary nucleophilic attack by water followed by decarboxylative elimination.
