1304522-75-5Relevant academic research and scientific papers
A ring closing metathesis-manganese dioxide oxidation sequence for the synthesis of substituted pyrroles
Keeley, Aaron,McCauley, Shane,Evans, Paul
, p. 2552 - 2559 (2016/04/26)
The combination of ring closing, or enyne metathesis with oxidation in order to prepare N-sulfonyl pyrroles is described. Reasonable to good yields were obtained for a variety of substituents and the procedure may also be conducted in one-pot. 2-Bromo N-sulfonyl adducts prepared in this manner were subjected to an intramolecular Heck-type cyclisation, forming cyclic sulfonamides.
Synthesis of vinylindoles and vinylpyrroles by the Peterson olefination or by use of the Nysted reagent
Noland, Wayland E.,Etienne, Christopher L.,Lanzatella, Nicholas P.
experimental part, p. 381 - 388 (2011/05/14)
Vinylindoles and vinylpyrroles were prepared from their corresponding aldehydes or ketones using the Peterson olefination, or by use of the Nysted reagent, a commercially available gem-dimetallic compound. The two methods provide efficient and convenient
