1304683-75-7Relevant academic research and scientific papers
A highly enantio- and diastereoselective molybdenum-catalyzed asymmetric allylic alkylation of cyanoesters
Trost, Barry M.,Miller, John R.,Hoffman Jr., Christopher M.
, p. 8165 - 8167 (2011/07/08)
An efficient molybdenum-catalyzed asymmetric allylic alkylation (Mo-AAA) of cyanoester nucleophiles is reported. A number of highly functionalized branched cyanoesters containing a quaternary carbon stereocenter with a vicinal tertiary stereocenter are obtained. This method generates a number of functionalized cyanoesters in excellent yield and chemoselectivity in good to excellent diastereoselectivity and enantioselectivity.
