1304780-03-7Relevant articles and documents
Syntheses of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid analogues modified by N-sulfonylamidino groups at the C-4 position and biological evaluation as inhibitors of human parainfluenza virus type 1
Nishino, Reiko,Ikeda, Kiyoshi,Hayakawa, Takuya,Takahashi, Tadanobu,Suzuki, Takashi,Sato, Masayuki
, p. 2418 - 2427 (2011/05/12)
Eleven novel sialidase inhibitors 9 and 10 with an N-sulfonylamidino group at the C-4 position of Neu5Ac2en 1 against human parainfluenza virus type 1 (hPIV-1) were synthesized using copper-catalyzed three-component coupling reactions, and their inhibitory activities against hPIV-1 sialidase were studied.