1304789-29-4

Basic information

• Product Name: 2-isopropyl-1-(phenylethynyl)-1H-imidazole
• Synonyms: 2-isopropyl-1-(phenylethynyl)-1H-imidazole
• CAS NO: 1304789-29-4
• Molecular Weight: 210.279
• Mol File: 1304789-29-4.mol

Chemical Properties

• CAS DataBase Reference: 2-isopropyl-1-(phenylethynyl)-1H-imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-isopropyl-1-(phenylethynyl)-1H-imidazole(1304789-29-4)
• EPA Substance Registry System: 2-isopropyl-1-(phenylethynyl)-1H-imidazole(1304789-29-4)

Safety Data

• Hazardous Substances Data: 1304789-29-4(Hazardous Substances Data)

Upstream product

• 36947-68-9 2-isopropylimidazole 
• 7436-90-0 2,2-dibromostyrene 
• 932-87-6 1-Bromo-2-phenylacetylene 

Relevant articles and documents

Copper(II) oxide catalyzed ligand-free coupling reaction of heteroarenes with bromoalkynes

The coupling reaction of imidazoles and pyrazoles with bromoacetylenes has efficiently been carried out under ligand-free conditions in the presence of copper(II) oxide as the catalyst using potassium hydroxide in 1,4-dioxane at 80 C. The method is a simpler access to N-alk-1-ynyl- and/or N-(2-bromovinyl)- substituted heteroarenes. Georg Thieme Verlag Stuttgart New York.

Copper-catalyzed coupling of imidazoles and pyrazoles with 1,1-dibromo-1-alkenes: A distinct approach for direct N-alkynylation of heteroarenes

The direct N-alkynylation of heteroarenes, imidazoles, and pyrazoles with 1,1-dibromo-1-alkene has been carried out for the first time using [Cu(Phen)PPh3Br] (as a catalyst) and Cs2CO3 in DMSO at 80 °C. The products are formed in good to high yields (66-85%) within 3 h. No side products could be detected.