1304789-30-7Relevant academic research and scientific papers
Copper(II) oxide catalyzed ligand-free coupling reaction of heteroarenes with bromoalkynes
Das, Biswanath,Reddy, Gandolla Chinna,Balasubramanyam, Penagaluri,Salvanna
experimental part, p. 816 - 820 (2011/04/25)
The coupling reaction of imidazoles and pyrazoles with bromoacetylenes has efficiently been carried out under ligand-free conditions in the presence of copper(II) oxide as the catalyst using potassium hydroxide in 1,4-dioxane at 80 C. The method is a simpler access to N-alk-1-ynyl- and/or N-(2-bromovinyl)- substituted heteroarenes. Georg Thieme Verlag Stuttgart New York.
