130481-59-3

Upstream product

• 130481-58-2 Benzoic acid 2-((1R,9S,10R,12R)-4-methyl-5-oxo-12-p-tolyloxythiocarbonyloxy-8,11-dioxa-2,6-diaza-tricyclo[7.2.1.0^2,7]dodeca-3,6-dien-10-yl)-ethyl ester 
• 14728-80-4 1,2:5,6-di-O-isopropylidene-3-O-(methylsulphonyl)-α-D-allofuranose 
• 64993-88-0 1,2-O-isopropylidene-3-O-methanesulfonyl-α-D-allofuranose 
• 130481-53-7 Benzoic acid (R)-2-((3aR,5R,6R,6aR)-6-methanesulfonyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-2-p-tolyloxythiocarbonyloxy-ethyl ester 
• 130481-52-6 Benzoic acid (R)-2-hydroxy-2-((3aR,5R,6R,6aR)-6-methanesulfonyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-ethyl ester 
• 130481-56-0 1-(2'-O-acetyl-6'-O-benzoyl-5'-deoxy-3'-O-mesyl-β-D-allofuranosyl)thymine 
• 130481-55-9 6-O-benzoyl-5-deoxy-1,2-di-O-acetyl-3-O-mesyl-α-D-allofuranose 
• 130481-57-1 2,3'-anhydro-1-(6'-O-benzoyl-5'-deoxy-β-D-glucofuranosyl)thymine 

Downstream Products

• 130481-61-7 1-(3'-azido-2',3',5'-trideoxy-β-D-allofuranosyl)thymine 
• 130481-60-6 1-(3'-azido-6'-O-benzoyl-2',3',5'-trideoxy-β-D-allofuranosyl)thymine 

Relevant academic research and scientific papers

Side-Chain Derivatives of Biologically Active Nucleosides. 1. Side-Chain Analogs of 3'-Azido-3'-deoxythymidine (AZT)

Starting from 3-O-mesyl-1,2-O-isopropylidene-α-D-allofuranose (9) the anomeric mixtures of the requisite carbohydrates 1,2-di-O-acetyl-6-O-benzoyl-5-deoxy-3-O-mesyl-D-allofuranoses 17Aα/β, 1,2-di-O-acetyl-5,6-di-O-benzoyl-3-O-mesyl-D-allofuranoses 17Bα/β,

1-(3′- Azido-2′, 3′, 5′ - trideoxy- β - d . Allofuranosyl) thymine a side-chain homologue of 3′- azido - 3′-deoxythymidine

1-(3′-Azido-2′,3′,5′-trideoxy-β-D- allofuranosyl)thymine 12 (homo-AZT) was synthesized starting from 1,2;5,6-di-O-isopropylidene- 3-O-mesyl-α-D-allofuranose 1 in an eleven step sequence (overall yield: 4%).