130486-85-0

Basic information

• Product Name: 2-Heptanone, 7-hydroxy-6-methyl-, (S)- (9CI)
• Synonyms: 2-Heptanone, 7-hydroxy-6-methyl-, (S)- (9CI)
• CAS NO: 130486-85-0
• Molecular Formula: C8H16O2
• Molecular Weight: 144.21144
• Product Categories: ACETYLGROUP
• Mol File: 130486-85-0.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Heptanone, 7-hydroxy-6-methyl-, (S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Heptanone, 7-hydroxy-6-methyl-, (S)- (9CI)(130486-85-0)
• EPA Substance Registry System: 2-Heptanone, 7-hydroxy-6-methyl-, (S)- (9CI)(130486-85-0)

Safety Data

• Hazardous Substances Data: 130486-85-0(Hazardous Substances Data)

Usage

Also known as

(S)-7-Hydroxy-6-methyl-2-heptanone

Classification

Ketone

Physical state

Clear liquid

Odor

Fruity, coconut-like

Uses

Flavoring agent, fragrance ingredient

Specific properties

Chiral form with specific optical rotation properties

Importance

Used in organic chemistry and asymmetric synthesis

Studied for

Potential biological activities such as being an insect pheromone and having antimicrobial properties

Upstream product

• 2436-90-0 (S)-(+)-dihydromyrcene 
• 130486-84-9 (+)-(S)-2-methyl-6-oxoheptanal 
• 220775-18-8 (S)-6-methyl-7-(2H-tetrahydropyran-2-yloxy)-heptan-2-one 

Relevant articles and documents

Biocatalysis at Work: Applications in the Development of Sagopilone

For the antitumour agent sagopilone, an epothilone analogue, a large-scale synthesis was developed to synthesise the active pharmaceutical ingredient for clinical trials, exploring enzymatic and microbial methods to produce chiral building blocks on a mul

Method for producing c1-c15 fragments of epothilones and the derivatives thereof

This invention describes a process for the production of C1-C15-fragments of epothilones and derivatives thereof, in which a C1-C6-fragment is linked with a C7-C12-fragment to a C1-C12-fragment, and the latter then is reacted with a C13-15-fragment to form the C1-C15 initial epothilone product that is to be produced. The thus obtained C1-C15 initial epothilone products can be reacted according to known methods to form the actual active ingredients. In addition, the invention relates to the corresponding C1-C12-fragments.

75. Enantiomeric 3,7-Dimethylocta-1,7-dienes as Useful Chiral Building Blocks. A New Access to Both Optical Antipodes of Natural (E)-3,7-Dimethyloct-2-ene-1,8-diol and (E)-3,7-Dimethyloct-2-ene-1,8-dicarboxylic Acid

Ozonolysis of the easily available monoterpenoids (-)-1 and (+)-1 leads in high yield to the keto-aldehydes (-)-4 and (+)-4, which serve as convenient intermediates for efficient new routes to both optical antipodes of the naturally occuring octene-diol (E)-2 (Monarch butterfly secretion product) and octene-dicarboxylic acid (E)-3 (Callosobruchus chinensis sex pheromone).All steps proceed with almost complete retention of configuration, ensuring the synthesis of the target compounds with high optical purity.