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1-(2,7-DIMETHYLPYRAZOLO[1,5-A]PYRIMIDIN-6-YL)ETHAN-1-ONE is a pyrazolopyrimidine derivative with the molecular formula C10H12N4O. It features a pyrazolopyrimidine ring with two methyl groups and a ketone functional group attached to an ethyl chain. This chemical compound is utilized in organic synthesis and medicinal chemistry as a building block for creating various pharmaceutical compounds. Its structural features and biological activity also suggest potential applications in drug discovery and development.

130506-85-3

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130506-85-3 Usage

Uses

Used in Pharmaceutical Synthesis:
1-(2,7-DIMETHYLPYRAZOLO[1,5-A]PYRIMIDIN-6-YL)ETHAN-1-ONE is used as a building block in the synthesis of pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic benefits.
Used in Drug Discovery and Development:
Due to its structural features and biological activity, 1-(2,7-DIMETHYLPYRAZOLO[1,5-A]PYRIMIDIN-6-YL)ETHAN-1-ONE is used in drug discovery and development processes. It may contribute to the creation of innovative medications for treating various diseases and conditions.
Used in Organic Synthesis:
1-(2,7-DIMETHYLPYRAZOLO[1,5-A]PYRIMIDIN-6-YL)ETHAN-1-ONE is used as a key intermediate in organic synthesis, enabling the production of a wide range of chemical compounds for various applications across different industries.

Check Digit Verification of cas no

The CAS Registry Mumber 130506-85-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,5,0 and 6 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 130506-85:
(8*1)+(7*3)+(6*0)+(5*5)+(4*0)+(3*6)+(2*8)+(1*5)=93
93 % 10 = 3
So 130506-85-3 is a valid CAS Registry Number.

130506-85-3 Well-known Company Product Price

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  • Alfa Aesar

  • (B20134)  3-Acetyl-4,6-dimethylpyrazolo(1,5-a)pyrimidine, 97%   

  • 130506-85-3

  • 1g

  • 564.0CNY

  • Detail

130506-85-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2,7-Dimethylpyrazolo[1,5-a]pyrimidin-6-yl)ethanone

1.2 Other means of identification

Product number -
Other names 6-acetyl-2,7-dimethylpyrazolo<1,5-a>pyrimidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:130506-85-3 SDS

130506-85-3Downstream Products

130506-85-3Relevant academic research and scientific papers

Synthesis, potency, and in vivo profiles of quinoline containing histamine H3 receptor inverse agonists

Altenbach, Robert J.,Liu, Huaqing,Banfor, Patricia N.,Browman, Kaitlin E.,Fox, Gerard B.,Fryer, Ryan M.,Komater, Victoria A.,Krueger, Kathleen M.,Marsh, Kennan,Miller, Thomas R.,Jia, Bao Pan,Pan, Liping,Sun, Minghua,Thiffault, Christine,Wetter, Jill,Zhao, Chen,Zhou, Deliang,Esbenshade, Timothy A.,Hancock, Arthur A.,Cowart, Marlon D.

, p. 5439 - 5448 (2008/03/13)

A new structural series of histamine H3 receptor antagonist was developed. The new compounds are based on a quinoline core, appended with a required basic aminoethyl moiety, and with potency- and property-modulating heterocyclic substituents. The analogs

Tri-and bi-cyclic heteroaryl histamine-3 receptor ligands

-

Page/Page column 34, (2010/02/14)

Compounds of formula (I) wherein R1 or R2 is a tricyclic or bicyclic ring, each of which contains at least two heteroatoms, and R1, R2, R3, R3a, R3b, R4, R5, L, X, X′, Y, Y′, Z, and Z′ are as defined herein, are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).

Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands

-

Page/Page column 34, (2010/02/14)

Compounds of formula (I) wherein R1 or R2 is a tricyclic or bicyclic ring, each of which contains at least two heteroatoms, and R1, R2, R3, R3a, R3b, R4, R5

A NEW ENTRY TO PYRAZOLOPYRIMIDINE DERIVATIVES

Bruni, Fabrizio,Chimichi, Stefano,Cosimelli, Barbara,Costanzo, Annarella,Guerrini, Gabriella,Selleri, Silvia

, p. 1141 - 1149 (2007/10/02)

Treatment of 3-aminopyrazoles (1a-e) with 3-ethoxymethylenpentane-2,4-dione afforded the new pyrazolopyrimidines (2a-e) which were then converted into the enamines (3a-e) by reaction with dimethylformamide dimethyl acetal; ring closure of these lat

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