1305285-52-2Relevant academic research and scientific papers
Synthesis of a new 4-aza-2,3-didehydropodophyllotoxin analogues as potent cytotoxic and antimitotic agents
Kamal, Ahmed,Suresh, Paidakula,Mallareddy, Adla,Kumar, Banala Ashwini,Reddy, Papagari Venkat,Raju, Paidakula,Tamboli, Jaki R.,Shaik, Thokhir B.,Jain, Nishant,Kalivendi, Shasi V.
, p. 2349 - 2358 (2011)
A series of novel conjugates of 4-aza-2,3-didehydropodophyllotoxins (11a-w) were synthesized by a straightforward one-step multicomponent synthesis that demonstrated cytotoxicity against five human cancer cell lines (breast, oral, colon, lung and ovarian)
4-AZA-2, 3-DIDEHYDROPODOPHYLLOTOXIN COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF
-
Page/Page column 21, (2012/06/30)
The present invention provides 4-Aza-2,3-didehydropodophyllotoxin compound of general formula A (4a- 4z and 4aa-4ae) as useful potential antitumour agents against human cancer cell lines. The present invention further provides a process for the synthesis
