13053-76-4Relevant articles and documents
Rearrangement Reaction Based on the Structure of N-Fluoro- N-alkyl Benzenesulfonamide
Wang, Han-Ying,Pu, Xiao-Qiu,Yang, Xian-Jin
, p. 13103 - 13110 (2018/10/20)
A novel rearrangement reaction based on the structure of N-fluoro-N-alkyl benzenesulfonamide was developed. The reaction proceeded readily at 50 °C in formic acid and generated a variety of benzenesulfonamides and aldehydes or ketones simultaneously. The reaction mechanism is believed to be a concerted mechanism that consist of 1,2-aryl migration with the departure of fluorine anion via an SN2 mechanism. This rearrangement reaction features an interesting reaction mechanism, mild reaction conditions, simple operations, and a broad substrate scope.