1305311-09-4Relevant articles and documents
Design and synthesis of amidine-type peptide bond isosteres: Application of nitrile oxide derivatives as active ester equivalents in peptide and peptidomimetics synthesis
Inokuchi, Eriko,Yamada, Ai,Hozumi, Kentaro,Tomita, Kenji,Oishi, Shinya,Ohno, Hiroaki,Nomizu, Motoyoshi,Fujii, Nobutaka
, p. 3421 - 3427 (2011)
Amidine-type peptide bond isosteres were designed based on the substitution of the peptide bond carbonyl (CO) group with an imino (CNH) group. The positively-charged property of the isosteric part resembles a reduced amide-type peptidomimetic. The peptidy