1305317-30-9

Basic information

• Product Name: 4-bromo-2-nitropyridin-3-amine
• Synonyms: 4-bromo-2-nitropyridin-3-amine
• CAS NO: 1305317-30-9
• Molecular Formula: C₅H₄BrN₃O₂
• Molecular Weight: 218.00816
• Mol File: 1305317-30-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 217-218 °C
• Boiling Point: 397.6±37.0 °C(Predicted)
• Appearance: /
• Density: 1.929±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -3.31±0.10(Predicted)
• CAS DataBase Reference: 4-bromo-2-nitropyridin-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-nitropyridin-3-amine(1305317-30-9)
• EPA Substance Registry System: 4-bromo-2-nitropyridin-3-amine(1305317-30-9)

Safety Data

• Hazardous Substances Data: 1305317-30-9(Hazardous Substances Data)

Usage

Description

4-bromo-2-nitropyridin-3-amine is a chemical compound with the molecular formula C5H4BrN3O2. It is a derivative of pyridine, featuring a nitro group at the 2 position and a bromine atom at the 4 position, with the amine group situated at the 3 position. 4-bromo-2-nitropyridin-3-amine is known for its potential applications across various fields, including medicine, agriculture, and materials science, primarily serving as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds.

Uses

Used in Pharmaceutical Industry:
4-bromo-2-nitropyridin-3-amine is used as a synthetic intermediate for the development of new pharmaceuticals. Its unique structure allows for the creation of various drug candidates that can target specific biological pathways or receptors, potentially leading to the discovery of novel treatments for a range of diseases.
Used in Agrochemical Industry:
In the agrochemical sector, 4-bromo-2-nitropyridin-3-amine is utilized as a building block in the synthesis of new agrochemicals. Its incorporation into these compounds can enhance their effectiveness in controlling pests, diseases, and weeds, thereby contributing to improved crop yields and food security.
Used in Materials Science:
4-bromo-2-nitropyridin-3-amine also finds applications in the field of materials science. Its chemical properties can be exploited to develop new materials with specific characteristics, such as improved stability, reactivity, or selectivity, which can be useful in various industrial processes.
Used in Research and Development:
4-bromo-2-nitropyridin-3-amine is employed as a key component in the research and development of new chemical entities. Its versatile structure allows scientists to explore its potential in various chemical reactions and transformations, leading to the discovery of innovative compounds with unique properties and applications.

Upstream product

• 13269-19-7 3-amino-2-nitropyridine 

Downstream Products

• 1232431-75-2 2,3-diamino-4-bromopyridine 
• 1305317-31-0 8-bromo-2,3-diphenylpyrido[2,3-b]pyrazine 
• 1305317-32-1 8-bromo-2,3-bis(4-methoxyphenyl)pyrido[2,3-b]pyrazine 
• 1305317-33-2 8-azido-2,3-diphenylpyrido[2,3-b]pyrazine 
• 1305317-34-3 8-azido-2,3-bis(4-methoxyphenyl)pyrido[2,3-b]pyrazine 
• 1305317-35-4 8-amino-2,3-diphenylpyrido[2,3-b]pyrazine 
• 1305317-36-5 8-amino-2,3-bis(4-methoxyphenyl)pyrido[2,3-b]pyrazine 
• 1305317-37-6 N-(2,3-diphenylpyrido[2,3-b]pyrazin-8-yl)-N'-ethylurea 
• 1305317-38-7 N-(2,3-diphenylpyrido[2,3-b]pyrazin-8-yl)-N'-phenylurea 
• 1305317-39-8 N-(3-chlorophenyl)-N'-(2,3-diphenylpyrido[2,3-b]pyrazin-8-yl)urea 
• 1305317-40-1 N-[2,3-bis(4-methoxyphenyl)pyrido[2,3-b]pyrazin-8-yl]-N'-ethylurea 
• 1305317-41-2 N-[2,3-bis(4-methoxyphenyl)pyrido[2,3-b]pyrazin-8-yl]-N'-phenylurea 
• 1305317-42-3 N-(2,3-diphenylpyrido[2,3-b]pyrazin-8-yl)-N'-ethylthiourea 
• 1305317-43-4 N-(2,3-diphenylpyrido[2,3-b]pyrazin-8-yl)-N'-phenylthiourea 

Relevant articles and documents

BIARYL KINASE INHIBITORS

The present disclosure is directed to biaryl compounds of formula (I) which can inhibit AAKl (adaptor associated kinase 1), compositions comprising such compounds and their use for treating e.g. pain, Alzheimer's disease, Parkinson's disease and schizophrenia.