13060-14-5

Usage

Uses

Used in Pharmaceutical Industry:
C10894 is used as a therapeutic agent for the treatment of hypogonadism and other hormonal imbalances. It is used for its ability to bind to and activate the androgen receptor, resulting in increased muscle mass and strength.
Used in Oncology:
C10894 is being investigated for its potential use in the treatment of breast cancer and other conditions related to hormone imbalances. Its mechanism of action involves binding to and activating the androgen receptor, which may have implications for the treatment of certain types of cancer.
Used in Orthopedics:
C10894 has been studied for its potential use in the treatment of osteoporosis, a condition characterized by a decrease in bone density and an increased risk of fractures. Its anabolic effects on bone tissue may help to improve bone health and reduce the risk of fractures in individuals with osteoporosis.
However, it is important to note that due to the potential for abuse and side effects, C10894 is a controlled substance and has limited medical use. Further research is needed to fully understand its potential applications and safety profile.

InChI:InChI=1/C24H30O8/c1-25-17-7-13(8-18(26-2)23(17)29-5)21-15-11-32-22(16(15)12-31-21)14-9-19(27-3)24(30-6)20(10-14)28-4/h7-10,15-16,21-22H,11-12H2,1-6H3/t15-,16-,21+,22+/m0/s1

Upstream product

• 487-35-4 (+)-syringaresinol 
• 77-78-1 dimethyl sulfate 
• 487-35-4 (+/-)-syringaresinol 
• 2373-80-0 3,4-methylenedioxy-trans-cinnamic acid 
• 20329-98-0 (E)-3,4,5-trimethoxy-cinnamic acid 
• 886989-84-0 (S)-1-[(E)-3-(3,4,5-trimethoxyphenyl)propenoyl]pyrrolidine-2-carboxylic acid 
• 886989-85-1 (1S,4S,5S,8S)-4,8-bis(3,4,5-trimethoxyphenyl)-3,7-dioxabicyclo[3.3.0]octane-2,6-dione 
• 886989-89-5 (1S,2R,3R,4S)-2,3-bis(hydroxymethyl)-1,4-bis(3,4,5-trimethoxyphenyl)butane-1,4-diol 

Downstream Products

• 60619-98-9 (+)-syringaresinol dimethyl ether 
• 24192-64-1 2,6-bis(3,4,5-trimethoxyphenyl)-3,7-dioxabicyclo[3.3.0]octane 

Relevant academic research and scientific papers

Electochemical asymmetric dimerization of cinnamic acid derivatives and application to the enantioselective syntheses of furofuran lignans

A new electrochemical method for the asymmetric oxidative dimerization of cinnamic acid derivatives has been developed. This method enabled the enantioselective syntheses of furofuran lignans, yangambin, sesamin and eudesmin.

Simple and efficient asymmetric synthesis of furofuran lignans yangambin and caruilignan A

A novel asymmetric dimerization of cinnamic acid derivative was achieved in high efficiency and high stereoselectivity. By using the reaction as a key step, two furofuran lignans, yangambin and caruilignan A were synthesized in optically pure form in only 5 and 6 steps, respectively. Georg Thieme Verlag Stuttgart.

Stereoselective total synthesis of furofuran lignans through dianion aldol condensation

Highly stereoselective total synthesis of (+)-eudesmin, (+)-yangambin, (-)-eudesmin, and (-)-yangambin is described. This method is useful to generate the core skeleton of furofuran rings utilizing modification of Evans asymmetric aldol condensation.

Photoinduced molecular transformations. 157. A new stereo- and regioselective synthesis of 2,6-diaryl-3,7-dioxabicyclo[3.3.0]octane lignans involving a β-scission of alkoxyl radicals as the key step. New total syntheses of (±)-sesamin, (±)-eudesmin, and (±)-yangambin

New total syntheses of naturally occurring 2,6-diaryl-3,7-dioxabicyclo[3.3.0]octane lignans, (±)-sesamin and (±)-eudesmin, and the first total synthesis of (±)-yangambin were achieved according to a general method devised by Suginome and colleagues for replacing the carbonyl group of the cyclopentanone ring with an oxygen atom to give a corresponding tetrahydrofuran ring involving a regioselective β-scission of alkoxyl radicals; arylation of dimethyl, diallyl, or dibenzyl 3,7-dioxobicyclo[3.3.0]octane-2,6-dicarbonate (18 and 19a,b) with aryllead triacetate 9a-c, followed by dealkoxycarbonylation of the resulting arylated product 20a-f, gave 2,6-diaryl-3,7-dioxobicyclo[3.3.0]octane 21a-c. A regioselective Baeyer-Villiger oxidation of 21a-c with m-CPBA-NaHCO3 or -K2CO3 gave the corresponding δ-lactone 22a-c, which was reduced with DIBAL to give the corresponding lactol 23a-c. The irradiation of a solution of the hypoiodite of 23a-c, generated in situ with mercury(II) oxide-iodine, in benzene with Pyrex-filtered light resulted in a regioselective β-scission of the corresponding alkoxyl radical to give iodo formate 24a-c. Heating 24a-c in MeOH with NaBH4 gave (±)-sesamin (25a), (±)-eudesmin (25b), or (±)-yangambin (25c).